Dapoxetine drug interactions and side effects
The disturbance in sexual function which makes the sexual act impossible due to very fast ejaculation is called premature ejaculation. It affects the process of getting sexual orgasm and breaks the natural process of response to sexual stimulation.
The orgasm phase of the sexual cycle in lots of men is inhibited by premature ejaculation. Most commonly PE is found in younger males. Still older ones can also suffer from this sexual health condition.
As premature ejaculation is a persistent ejaculation problem occurring with minimal sexual stimulation before or after penetration, it needs proper treatment.
One of the most effective drugs today is Dapoxetine manufactured under the brand name Priligy. Dapoxetine was studied in one phase 2 and two phase 3 trials, all showing significant success in extension the period before having orgasm.
About 166 adult males participated in the trials. All the patients experienced some type of premature ejaculation. The participants were divided into several groups receiving 30 mg, 60 mg and 100 mg of Dapoxetine and one group receiving placebo.
130 patients finished the trials and the groups taking Dapoxetine demonstrated substantial improvement in the time before ejaculating.
Among the most common side effects reported by men were nausea, headaches, and stomach problems. The side effects tend to disappear when the body gets accustomed to the action of the medicine. The other side effects are: dizziness, diarrhea, sleepiness are very rare.
Today there is no evidence of drug interactions with Dapoxetine. The medicine does not interact with alcohol and food. It can be taken with PDE type 5 inhibitors including Cialis, Levitra and Viagra.
As there is no information about the drug interactions with this medicine, a person can ask a doctor about possibility to use Dapoxetine with other drugs. Before getting the treatment with this medicine it is urgent to consult a doctor.
The trials of the medicine suggest that Dapoxetine is an effective, safe and well tolerated method of premature ejaculation treatment. It is used on demand by mouth. No significant side effects and drug interactions are noticed with Dapoxetine.
The long use of this medicine is proven to be beneficial for premature ejaculation better management.
By meeting the needs of men with early ejaculation, Dapoxetine helps to increase the time of sexual act, improve the relations between couples, and enhance the self-esteem and confidence of a man.
The use of Dapoxetine is very common today. Lots of men order this medicine online without prescription. Still it is an antidepressant by its nature, that is why a proper use and consultation with a medical professional are needed.
Medical treatment of premature ejaculation
The medical treatment of PE involves using of special medicines which delay the ejaculation process. These medicines are SSRIs antidepressants. They are used off-label as they are not approved by the FDA. The medicines which are often prescribed for PE are: paroxetine, sertraline, fluoxetine, citalopram and fluvoxamine, and the serotonergic tricyclic clomipramine.
The appearance of Dapoxetine on the market has radically changed the treatment of PE. This medicine has shown welcome results in preventing early ejaculations and giving men longer periods in bed. Dapoxetine is also a SSRI with the properly to stop the reuptake of serotonin from the synapse by 5-HT transporters, resulting in enhanced 5-HT neurotransmission, stimulation of postsynaptic membrane 5-HT2C receptors. This characterisitic of the medicine helps in ejaculatory delay and more control over ejaculations. The use of antidepressants for the treatment of PE has become very common. Still many men fear to use these drugs. About 30% of men discontinue the treatment only due to the worries of side effects.
Dapoxetine belongs to the short-acting medicines meaning that the medicine is quickly eliminated from the body and does not cause any harm to the health in the short or long period. Men who start using Dapoxetine, report full satisfaction with the results of the treatment. They say the time to ejaculation gets longer, that they get more control over early climaxing.
PE and its symptoms
Premature ejaculation PE is a medical state when a male gets an orgasm too quickly and ejaculates too early without control. Generally speaking, ejaculation in PE occurs very quickly before the necessary time or before a man and his partner wants it to occur. Some men ejaculate as soon as they penetrate, others ejaculate before penetration.
Commonly, all men with PE have a lot of personal suffering due to inability to satisfy their partners sexually. According to special PE research, practically all men experience early ejaculation at some point in their lives. Usually, younger men, who just start sexual experience and need to learn how to control their ejaculation, are the sufferers of early climaxing. Most of such men get the knowledge of how to control their body. Those who cannot manage this condition by themselves should get a medical treatment or use certain techniques. Some men can have a lifelong premature ejaculation. It means that they have this problem during a whole period of time. Others may develop this condition due to emotional problems, mental health issues and other factors such as stress. Other reasons behind the PE can be inflammation of the prostate gland or a spinal cord problem. The symptoms of PE include: • Early uncontrolled ejaculation; • Ejaculation which occurs soon after penetration; • Inability to have sexual pleasure because of PE; • Depression, anxiety, embarrassment and frustration due to the PE problem. Nevertheless what the cause of the problem is and what symptoms you experience, it is necessary to get the proper treatment which will improve the situation with ejaculation control and make better sexual life.